Rhabdomyolysis



Causes

Trauma

  • Prolonged immobilisation
  • Burns
  • Crush injury
  • Excessive exercise (beware new "spinning")
  • Seizures

Drugs and Toxins

  • Statins
  • Alcohol
  • Ecstasy, cocaine, amphetamines
  • Heroin and methadone
  • Steroids
  • Propofol (infusion ± inotropes)

Snake bite (very common in Ireland!)

Carbon monoxide

Neuroleptic malignant syndrome

Infections

  • Coxsackie virues
  • EBV
  • Influenza
  • Tetanus

    Metabolic

    • Hypokalaemia, ↓ phosphate
    • Myositis
    • Malignant hyperpyrexia

    Inherited disorders

    • McArdle's / Tarui disease (glucose metabolism)
    • Duchenne's muscular dystrophy


Content By Dr PJ Whooley 12/10/2018. Last review Dr ÍOS 13/11/18.