Stroke CUH

Background

CUH has the biggest inpatient stroke service in Ireland
It is one of two thrombectomy centres in the country
Your role is to recognise acute stroke patients that may be suitable for acute intervention
The Stroke Reg is in-house every day until 8pm and a Consultant on call 24/7. Please call them

Alteplase (stroke) dosing
Weight (Kg)	Total rTpa dose (mg)	10% bolus (mL)	90% IV infusion (mL/hr)	No. of 50mg rt-PA vials needed
40	36	4	33	1
42	38	4	34	1
44	40	4	36	1
46	41	4	37
48	43	4	39	1
50	45	5	40	1
52	47	5	42	1
54	49	5	44	1
56	50	5	45	2
58	52	5	47	2
60	54	5	49	2
62	56	6	50	2
64	58	6	52	2
66	59	6	53	2
68	61	6	55	2
70	63	6	57	2
72	65	6	59	2
74	67	7	60	2
76	68	7	61	2
78	70	7	63	2
80	72	7	65	2
82	74	7	67	2
84	76	8	68	2
86	77	8	69	2
88	79	8	71	2
90	81	8	73	2
92	83	8	75	2
94	85	8	77	2
96	86	9	77	2
98	88	9	79	2
100	90	9	81	2
1. Total dose: 0.9mg/kg.Max. dose is 90 mg 2. Admin. of Alteplase should be sanctioned by the physician on call for stroke 3. 10% of total dose given as IV push over 2 minutes 4. Remaining 90% of dose IV over 60 minutes via infusion pump