DOB - Dimethoxy Bromoamphetamine



Background

NACD Advisory about DOB.

  • White tablets without any logo have appeared in Ireland.
  • Taken as Ecstasy, these tablets actually contain DOB - Dimethoxy Bromoamphetamine.
  • This was first made in the late 1960's.
  • Street name "Snowballs" .
  • White tablets, No logo.
  • Slightly smaller than MDMA, more rounded at the edges.

Pharmacology & Clinical

  • Potent hallucinogenic amphetamine (different to Ecstasy).
  • May take up to 3 hours to have an effect (last from 8 to 24 hours) so people take more expecting early effect.

Clinical effects

  • Energising effect & very pronounced hallucinations (v different to E).
  • Risks of delusional behaviour and psychotic reactions.
  • Larger doses - memory loss, irrational violence / self-harm.
  • Vascular spasm can result in limb gangrene

Suspect in patient who is agitated or who hallucinates after taking "ecstacy"


Management

  • Agitation treated with benzodiazepines
  • Heparin ± nitroprusside for spasm


Content by Dr Íomhar O' Sullivan, Received from NACD on 23/10/ 2003. Reviewed br Dr ÍOS 12/12/2003, 10/08/2004, 18/05/2005, 15/05/2007. Last review Dr. ÍOS 19/09/14.