Peyronie's Disease

Background

• 40-70 yo, penis is deviated during an erection
• The deviation is caused by a plaque (scar tissue) in the shaft of the penis
• There may be a history of trauma but most often there is no obvious cause
• The penis appears normal when it is flaccid but a plaque can usually be felt on the shaft of the penis during physical exam
• "Acute" inflammatory phase (18 months) = tender penile nodule ± curvature
• Most progress to the "chronic" phase with angulation / scarring ±calcification, ± impotence

Management

• All patients need a referral to a urologist
• Many patients are placed on medication during a period of observation
• Vitamin E, Ca⁺⁺ channel blockers and Potaba
• Surgery is indicated only if the disease is interfering with sexual function
• Surgery is simple and can be done as an outpatient