Pertussus - whooping cough



Background

  • Bordetella pertussis
  • Bacterial LRTI with paroxysmal cough ±whoop
  • Humans the only reservoir

Clinical

1st stage (1-2 weeks) - "catarrhal"

  • Nasal congestion & rhinorrhea
  • Low-grade (if any) pyrexia
  • Conjunctival suffusion

2nd Stage – "paroxysmal"

  • Paroxysms of intense dry coughing then whoop
  • ± vomiting with cough
  • Scleral hemorrhages due to coughing

3rd stage - "convalescence"

  • Chronic cough - weeks

Differential Dx


Management

  • Suportive
  • Azithromycin/clarithromycin
  • Prevention & Immunisation
    • DTaP or Tdap vaccine
    • Consider AB prophylaxis in susceptible contacts

Investigations

  • B pertussis on C&S (NPA)
    • 80% sensitive
  • PCR


Content by Dr Íomhar O' Sullivan. Last review Dr ÍOS 16/02/25.