Pertussus - whooping cough



Background

  • Bordetella pertussis
  • Bacterial LRTI with paroxysmal cough ±whoop

Clinical

1st stage (1-2 weeks) - "catarrhal"

  • Nasal congestion & rhinorrhea
  • Low-grade pyrexia
  • Conjunctival suffusion

2nd Stage – "paroxysmal"

  • Paroxysms of intense coughing then whoop
  • ± vomiting with cough

3rd stage - "convalescence"

  • Chronic cough - weeks

Differential Dx

Investigations

  • B pertussus grown on C&S (nasopharyngeal aspirate)
  • PCR available

Management

  • Suportive
  • Erythromycin, clarithromycin, or azithromycin
  • Prevention : Immunisation
    • DTaP or Tdap vaccine


Content By Dr Íomhar O' Sullivan 18/03/2016. Last review Dr ÍOS 10/06/21.