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DDx critera for "benign" lytic bone lesions

F E G N O M A S H I C

Fegnomashic
F Fibrous dysplasia No periosteal rxn. If in tibia mention adamantinoma.
E Echondroma
Eosinophilic granuloma
Must have calcification, except in phalanges. No periostitis.
E. Granuloma must be under 30
G Giant cell tumour (1)Epiphysis closed (2)Must abut the articular surface (3)Eccentric (4)Well defined, non-sclerotic border
N Nonossifying fibroma Must be under 30. No periostitis
O Osteoblastoma DDx ABC over 30 years
M Mets or myeloma Over 40
A Aneyrysmal bone cyst ABC must be under 30. Expansile.
S Solitary bone cyst Must be centrally located, under 30.
H Hyperparathyroidism "Brown tunour". Other evidence of hyperparathyroidism
I Infection If adjacent to joint, "must" involve joint
C Chondroblastoma
Chondromyxoid fibroma
Must be under 30. Epiphyseal
DDx nonossifying fibroma


Content by Dr Íomhar O' Sullivan. Last review Dr ÍOS 7/03/23.