Anti D immunisation



Background

Use during pregnancy:

The following episodes may be associated with significant foeto-maternal haemorrhage during pregnancy

  • Abdominal trauma(Rh negative women only)
  • chorionic villus sampling
  • amniocentesis
  • external cephalic version
  • antepartum haemorrhage
  • ectopic pregnancy
  • abortion
  • caesarian section

Management

  • In CUH, we stock 1500 IU doses (Rhophylac®) and we issue at least 1 x 1500 IU dose of anti-D for all potentially sensitising events (PSE) regardless of gestation, which must be administered within 72 hours of the PSE.
  • More than one dose may be given for a PSE after 20 weeks, if indicated by the Kleihauer results and we administer 1 x 1500 IU dose for every 12 ml of fetal cells detected.


Content by Dr Íomhar O' Sullivan. Last review Dr ÍOS 27/05/21.