Metaraminol preparation


Preparation

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Metaraminol preparation
Indication Details
Form 10mg/mL ampoule
Reconstitution Already in solution
Compatibility G5 or NS
Administration:

IV injection

Metaraminol Compatible fluid Final conc.
1mL 19mL 500 cmg/mL

In an emergency, give 500mcg - 1000mcg (1-2ml) bolus slowly over 2-5

IV infusion

Metaraminol Compatible fluid Final conc.
2mL 38mL 500 cmg/mL

IV infusion

Administer via an infusion pump at a rate up to 10mg/hour (20mL/hour of 500microgram/mL). If a central venous access device is unavailable, administer via a large peripheral vein monitoring insertion site. Resite cannula at first signs of inflammation.

After discontinuation, flush the peripheral cannula with sodium chloride 0.9% at the same rate the medicine was infused to avoid an unintentional 'bolus' dose. Discard the IV administration set administration set before flushing the cannula.

Peripheral cannula: Flush if it is to remain in situ. Central venous access device: Aspirate the cannula contents before flushing.

Monitoring Monitor BP, HR, ECG, CVP, drowsiness, UO, K+, lactate
Extravasation This medicine has a low pH and may cause venous irritation and tissue damage in cases of extravasation
Additional
  • Change the syringe every 24 hours
  • On set of action is around 1 – 2 minutes and a single dose lasts from 20 minutes to 1 hour. There is no need to piggyback infusions
  • Maximum effects are not immediately apparent: at least 10 minutes should elapse between dose increases
Information relates to Metaraminol manufactured by Torbay & South Devon NHS Foundation Trust

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Content by Dr Íomhar O' Sullivan, Regina Lee. Last review Dr ÍOS Regina Lee 5/04/23.