EMed

Phenylephrine

Preparation

Print version

Phenylephrine preparation
Indication: Acute hypotension
Form: 10mg per 1ml ampoule
Reconstitution: Already in solution but dilute before administration.
Administration: Peripheral or central IV route
Dilute 10mg (1ml of 10mg/ml solution) to 100ml saline to give a 100 microgram/ml solution.
Compatible: Sodium chloride 0.9% or DW5
Adminstration:

Dilute 10mg (1mL of a 10mg/mL solution) to 100mL compatible infusion fluid to give a 100 microgram/mL solution.

IV Injection: Usual bolus = 0.1mg - 0.5mg.
Withdraw the required amount from the prepared solution. Administer prescribed solution over 3-5 minutes. Injections should be repeated no more than every 15 minutes.

Continuous IV Infusion, peripheral or central IV route
Initial maximum rate 180 microgram/minute, adjusted to 30-60 microgram /minute according to response, via rate controlled infusion pump or syringe pump.
Special notes: Extravasation may cause tissue necrosis. If a central venous access device is unavailable, administer via a large peripheral vein monitoring insertion site closely. Re-site cannula at first signs of inflammation.
Information provided relates to Phenylephrine manufactured by Beacon Pharmaceuticals.

Print version

Content by Dr Íomhar O' Sullivan, Regina Lee. Last review Dr ÍOS Regina Lee 12/04/23.