Tear Gas (and Pepper Spray)



CS and CN Structures
CS and CN Structures
capsaicin structure
Capsaicin structure

Background

  • Chemical irritant
  • Either powder or 1% - 5% aerosol spray
  • Commonest used are
    • chlorobenzylidene-malononitrile
    • (CS after chemists Corson and Stoughton)
    • chloroacetophenone (CN or "Mace")
    • dibenzoxazepine (CR)
    • oleoresin capsicum (OC)
    • pelargonic acid vanillylamide (PAVA)
  • Pepper strength is measured in Scoville heat units
    • Green pepper = 0, pure capsaicin = 15 million units
  • Irritant effect from action of chlorine or cyanide groups
  • Immediate release of inflammatory P substance
  • Effects enhanced by heat and by high humidity
  • Rapid onset time & short duration of effects
  • Wide margin of safety between the incapacitating dose (ICt 50, the concentration (C) that causes incapacitation (I) in 50% of individuals after one minute (t=time)) and the lethal dose (LCt 50, the concentration that causes death (L) in 50% of individuals after one minute)

Clinical

Clinical manifestations and potential complications
Area Clinical Complications Potential sequelae

Eyes

Tearing, burning sensation, blepharospasm, photophobia, corneal oedema Keratitis, corneal erosion, intraocular haemorrhage Cataract, glaucoma

Area

Severe rhinorrhoea, sneeze, cough, dyspnoea, pharyngitis, bronchitis Bronchospasm, hypoxia, delayed pulmonary oedema Asthma

CVS

Hypertension Heart failure, cerebral haemorrhage

Skin

Rash, oedema, erythema, blistering Irritant dermatitis, facial oedema Allergic dermatitis

GIT

Buccal irritation, salivation, abdo. pain, D&V Liver toxicity  

Neuro

Trembling, agitation, anxiety

Diphoterine
Diphoterine

Management

  • Medical teams should wear protection for their own safety and to prevent secondary contamination
  • Contaminated clothes removed; eyes and affected skin surfaces should be cleaned with water
  • For pulmonary symptoms, oxygen therapy, β2-mimetics and ipratropium aerosols may be required
  • For pulmonary symptoms, a 24-48 hour stay in CDU may be required
  • Remove contact lenses
  • Irrigate eyes with saline or Diphoterine (in storage cupboard, decontamination room CUH)
  • Wash skin with soap and water or Diphoterine (in storage cupboard, decontamination room CUH)
  • Severe skin lesions - wash then topical steroids


Content by Dr Íomhar O' Sullivan. Last review Dr ÍOS 25/06/22.