Anticholinergic
Blind as a bat, mad as a hatter, red as a beet, hot as a hare, dry as a bone, the bowel and bladder lose their tone, and the heart runs alone.
Clinical
- Blurred vision, dry skin, fever, flushing
- Ileus, urinary retention
- Tachycardia, hypertension, hyperthermia
- Mydriasis, myoclonus, seizures
- Coma, delirum, hallucinations, amnesia
Causes
- Antihistamines
- Antipsychotics, antidepressants>
- Antiparkinsonian drugs
- Atropine, benztropine.
Cholinergic
DUMBBELLSS: Diarrhoea, Urination, Miosis, Bradycardia, Bronchospasm, Emesis, Lacrimation, Lethargy, Salivation and Seizures.
Most deaths from ⇓HR, & bronchospasm/bronchorrhoea.
Clinical
- Bronchorrhoea, tachypnoea, diaphorsesis
- Salivation, emesis, lacrimation, diarrhoea
- Confusion, meiosis, fasciculations, seizures, urination, & weakness
- Complications include ⇓HR, ↓Temp., ⇑RR
Causes
- Organophosphates
- Nerve agents (e.g. Sarin)
- Mushrooms