Mercy University Hospital Antidote List
A - required to be immediately available (within the ED)
B - required to be available within 1 hour (within the hospital)
C - rarely used and can be held supra-regionally
| Drug | Indication | Req. | PPT | Minimum Quantity | Location | Comment |
|---|---|---|---|---|---|---|
| Andexanat Alfa more |
Reversal of anticoagulation from apixaban/rivaroxaban | B | Ondexxya 200mg vial | 3 packs of 4x 200 mg vials | Pharmacy Fridge | Second shelf from bottom in Fridge 2 in Pharmacy |
| Acetylcysteine more |
Paracetamol | A | Parvolex 2g in 10ml amp | 10 amps | Antidote box | More in Drug Room in ED and in injection room in Pharmacy |
| Activated charcoal | Most oral poisons | A | Carbomix 50g granules | 1 x 50g | Antidote box | More in Drug Room in ED and in Pharmacy (near oral liquids) |
| Atropine sulphate | Organophosphate and carbamate insecticides | A | 600mcg/ml amps | 10 amps | Antidote box | More in Drug Room in ED and in injection room in Pharmacy |
| Benzylpenicillin | Amatoxin poisoning | A | Crystape 600mg vials | 25 vials | ED Drug room | More in injection room in Pharmacy |
| Calcium Chloride |
Ca++ Channel blockers HF |
A | 10%w/v PFS for slow infusion | 1 pre-filled syringe | Antidote box | More in injection room in Pharmacy |
| Calcium gluconate | Hydrofluoric acid | A | 10% 10ml amps | 10 amps | Antidote box | More in injection room in Pharmacy |
| Calcium Gluconate (CF) 2.5% Gel | Hydrofluoric acid burns < 5% of body surface or exposures to concentrations of less than 20% hydrofluoric acid | A | HF Antidote Gel (Calcium gluconate 2.5% gel) | 2 x 25g tubes | Antidote box | |
| Cholestyramine | Oral anti-coagulants | B | JAMP Cholestryamine 4g sachets | 3 sachets | Antidote box | More in Pharmacy (near oral liquids) |
| Cyproheptadine | Serotonin syndrome | B | Periactin 4mg tabs | 10 tabs | Antidote box | More in Pharmacy |
| Dantrolene (Dantrium) | Neuroleptic Malignant Syndrome | B | 20mg vial | 12 | Theatre | Very expensive – stored in theatre. CUH stock in CD/DDA press in Resusc |
| Desferrioxamine (Desferal) |
Iron | B | 500mg vial | 20 vials | Antidote box | More in injection room in Pharmacy |
| Diazepam (Diazemuls) | Convulsions, agitation | A | 10mg/2ml amps | 10 amps | Antidote box | More in injection room in Pharmacy |
| DigiFab | Digoxin toxicity | A | 40mg/4ml | 6 | Pharmacy Fridge | One additional vial stored in fridge in CCU. CUH stock in Resusc Fridge |
| Dehydrated alcohol (Ethanol) | Ethylene glycol and methanol (more) | A | 5ml amps | 30 amps | Antidote box | Fomepizole to be used first line. |
| Flumazenil | Benzodiazepine OD | A | 5ml amps | 10 amps | Antidote box | More in injection room in Pharmacy |
| Folinic Acid (Calcium leucovorin) |
Methotrexate, methanol & formic acid toxicity | B | 300mg vial | 1 | Pharmacy Fridge | More in fridge in St Therese's Day Ward |
| Fomepizole (Antizol) | Ethylene glycol and methanol | B | 1.5ml vial | 4 vials | Antidote box | Very expensive! More stored in pharmacy on IV shelves |
| Glucagon hypokit | Beta & calcium channel blockers, hypoglycaemia | A | Hypokit | 5 syringes | Fridge in ED Resusc | More in the Fridge in ED Clean Utility and in fridge in Pharmacy |
| Idarucizumab (Praxbind) | Dabigatran | B | 2.5g/50ml vial | 2 | Pharmacy Fridge | Very expensive |
| Intralipid | Lidocaine toxicity | A | 20% w/v 500ml emulsion for infusion | 2 bags | Antidote box | More in pharmacy or stock on theatre |
| Mesna | Cyclophosamide or Ifosfamide toxicity | B | 1g/10ml amps | 15 | Pharmacy | On shelf below Cytotoxic drug press |
| Methylene blue | Treatment of methaemoglobinaemia | A | 50mg/10ml amps | 5 amps | Antidote box | More in injection room in Pharmacy |
| Naloxone | Opioid overdose | A | 400mcg/1ml amps | 25 amps | Antidote box | More in injection room in Pharmacy |
| Octreotide | ↓Glu from sulphonylureas & quinine |
B | 50mcg amps | 2 | Pharmacy Fridge | |
| Penicillamine | Lead, copper and arsenic poisoning | C | 250mg tabs | 100 tabs | Antidote box | Also stored in CUH - stock in CD/DDA press in Resusc |
| Phentolamine (Rogitine) |
Hypertension caused by MAOIs or Clonidine or cocaine ingestion | A | 10mg/ml amps | 5 | Fridge in Main Theatre | Theatre |
| Phytomenadione (Vitamin K) |
Vitamin K dependent anticoagulants | B | 10mg/ml amps | 10 amps | Antidote box | More in injection room in Pharmacy |
| Polyethylene glycol (Klean-prep) |
Gut decontamination for lithium and iron | B | Sachets | 8 sachets | Antidote box | More in Pharmacy (stored with oral liquids) |
| Pralidoxime | Organophosphorus insecticides | C | 1g injection | 6 | CUH | Stored in CUH - stock in CD/DDA press in Resusc |
| Procyclidine (Kemadrin) | Dystonic reactions caused by antipsychotics and metoclopramide | A | 10mg/2ml amps | 5 amps | Antidote box | More in St Michael's Unit |
| Protamine | Heparin poisoning | A | 10mg/ml amps | 10 amps | Antidote box | More in injection room in Pharmacy |
| Prussian Blue | Thallium poisoning | C | Capsules | 250mg/kg/day p.o. | CUH | Stored in CUH - stock in CD/DDA press in Resusc |
| Pyridoxine | Isoniazid toxicity | A | 100mg/2ml amps | 50 amps | Antidote box | Also stored in CUH - stock in CD/DDA press in Resusc |
| Sodium bicarbonate 8.4% and 1.26% or 1.4% | Aspirin/Tricyclic antidepressant toxicity | A | 100ml 8.4% bottles | 3 bottles | Antidote box | More in injection room in Pharmacy |
| Sodium thiosulphate | Cyanide toxicity | A | 10g/20ml amps | 5 amps | Antidote box | Also stored in CUH - stock in CD/DDA press in Resusc |
| Starch | Iodine | A | Powder | 15g | Antidote box |